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Zebrafish mutants reveal unexpected role of Lrp5 in osteoclast regulation
Iryna Khrystoforova
, Chen Shochat-Carvalho
, Ram Harari
, Katrin Henke
, Katherine Woronowicz
, Matthew P. Harris
,
David Karasik
Bar-Ilan University - Azrieli Faculty of Medicine
Emory University
Boston Children's Hospital
Harvard University
Research output
:
Contribution to journal
›
Article
›
peer-review
14
Scopus citations
Overview
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Keyphrases
Low-density Lipoprotein Receptor-related Protein 5 (LRP5)
100%
Osteoclast
100%
Zebrafish mutant
100%
Zebrafish
33%
Tartrate-resistant Acid Phosphatase
22%
Matrix metalloproteinase-9 (MMP-9)
22%
Gene Expression
11%
Bone Formation
11%
Gain-of-function mutation
11%
Adult Age
11%
Enrichment Analysis
11%
Human Disease
11%
Homeostasis
11%
Transcriptome Analysis
11%
Bone Mineral Density
11%
Osteogenesis
11%
Missense mutation
11%
Low Bone Mass
11%
Genetic Determinants
11%
Bone Resorption
11%
Lipoprotein Receptor-related Protein
11%
Low Bone Mineral Density
11%
Co-receptor
11%
Knock
11%
Gain-of-function
11%
Disease Research
11%
Zebrafish (Danio rerio) Embryo
11%
Bone Homeostasis
11%
Human Losses
11%
High Bone Mass
11%
Resorption
11%
Matrix metalloprotease-9
11%
Osteoclast Function
11%
Mass Disorder
11%
Osteoporosis-pseudoglioma Syndrome
11%
Cranium
11%
Skeletogenesis
11%
Wnt Ligands
11%
Dysmorphology
11%
Hydrolase Activity
11%
Osteoclast Differentiation
11%
Total Head
11%
Craniofacial Deformities
11%
Popular
11%
Total-body
11%
Biochemistry, Genetics and Molecular Biology
Zebra Fish
100%
Osteoclast
100%
Tartrate-Resistant Acid Phosphatase
33%
Homeostasis
33%
Bone Development
33%
Bone Density
33%
Bone Mass
33%
Lipoprotein Receptor-Related Protein
33%
Genetics
16%
Hydrolase
16%
Gene Expression Profiling
16%
Dynamics
16%
Co-Receptor
16%
Missense Mutation
16%
Upregulation
16%
Ossification
16%
Loss of Function Mutation
16%
Osteoclastogenesis
16%
Osteolysis
16%
Metalloproteinase
16%
LDL Receptor
16%