Yeast and Human Nuclear Pore Complexes: Not So Similar After All

Yaron Shav-Tal; Timir Tripathi

doi:10.1016/j.tcb.2018.06.004

Yeast and Human Nuclear Pore Complexes: Not So Similar After All

Yaron Shav-Tal
, Timir Tripathi

The Mina and Everard Goodman Faculty of Life Sciences - at Bar-Ilan University

North-Eastern Hill University India

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

Nucleoporin subunits that generate the nuclear pore complex (NPC) are highly conserved in evolution. High-resolution structures of the NPC are available, but the actual NPC composition in yeast has only been quantified recently. Two studies reveal major differences between species, suggesting high flexibility in NPC structures during evolution.

Original language	English
Pages (from-to)	589-591
Number of pages	3
Journal	Trends in Cell Biology
Volume	28
Issue number	8
DOIs	https://doi.org/10.1016/j.tcb.2018.06.004
State	Published - Aug 2018

Bibliographical note

Publisher Copyright:
© 2018 Elsevier Ltd

Funding

Y.S-T. and T.T. are supported by a joint India University Grant Commission (UGC) and Israel Science Foundation (ISF) grant. We are grateful to Rakefet Ben-Yishay (BIU) and Parismita Kalita (NEHU) for generating the figure.

Funders
Parismita Kalita
Rakefet Ben-Yishay
North-Eastern Hill University
University Grants Committee
Israel Science Foundation
joint India University Grant Commission

Keywords

NPC structure
evolution
nuclear pore complex
nucleoporins

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10.1016/j.tcb.2018.06.004

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title = "Yeast and Human Nuclear Pore Complexes: Not So Similar After All",

abstract = "Nucleoporin subunits that generate the nuclear pore complex (NPC) are highly conserved in evolution. High-resolution structures of the NPC are available, but the actual NPC composition in yeast has only been quantified recently. Two studies reveal major differences between species, suggesting high flexibility in NPC structures during evolution.",

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KW - evolution

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Yeast and Human Nuclear Pore Complexes: Not So Similar After All

Abstract

Bibliographical note

Funding

Keywords

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