Yeast and Human Nuclear Pore Complexes: Not So Similar After All

Yaron Shav-Tal, Timir Tripathi

Research output: Contribution to journalShort surveypeer-review

5 Scopus citations

Abstract

Nucleoporin subunits that generate the nuclear pore complex (NPC) are highly conserved in evolution. High-resolution structures of the NPC are available, but the actual NPC composition in yeast has only been quantified recently. Two studies reveal major differences between species, suggesting high flexibility in NPC structures during evolution.

Original languageEnglish
Pages (from-to)589-591
Number of pages3
JournalTrends in Cell Biology
Volume28
Issue number8
DOIs
StatePublished - Aug 2018

Bibliographical note

Publisher Copyright:
© 2018 Elsevier Ltd

Keywords

  • NPC structure
  • evolution
  • nuclear pore complex
  • nucleoporins

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