Welcome to the nucleus: CAN I take your coat?

A. Harel; D. J. Forbes

doi:10.1038/ncb1201-e267

Welcome to the nucleus: CAN I take your coat?

A. Harel, D. J. Forbes

University of California at San Diego

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Individual viruses have evolved strategies for surmounting a formidable barrier in their path to replication in the nucleus - the nuclear envelope. A new study describing the nuclear entry of adenovirus 2 finds that this virus docks at the CAN/Nup214 protein of the nuclear pore, then hijacks histone H1 and specific H1-import receptors to effect a targeted uncoating of its nucleocapsid at the nuclear pore.

Original language	English
Pages (from-to)	E267-E269
Journal	Nature Cell Biology
Volume	3
Issue number	12
DOIs	https://doi.org/10.1038/ncb1201-e267
State	Published - Dec 2001
Externally published	Yes

Funding

Funders	Funder number
National Institute of General Medical Sciences	R01GM033279

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10.1038/ncb1201-e267

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Welcome to the nucleus: CAN I take your coat?

Abstract

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