Weighted LCS

Amihood Amir, Zvi Gotthilf, B. Riva Shalom

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

The Longest Common Subsequence (LCS) of two strings A and B is a well studied problem having awide range of applications. When each symbol of the input strings is assigned a positive weight the problem becomes the Heaviest Common Subsequence (HCS) problem. In this paper we consider a different version of weighted LCS on Position Weight Matrices (PWM). The Position Weight Matrix was introduced as a tool to handle a set of sequences that are not identical, yet, have many local similarities. Such a weighted sequence is a 'statistical image' of this set where we are given the probability of every symbol's occurrence at every text location. We consider two possible definitions of LCS on PWM. For the first, we solve the weighted LCS problem of z sequences in time O(znz+1). For the second, we prove NP-hardness and provide an approximation algorithm.

Original languageEnglish
Title of host publicationCombinatorial Algorithms - 20th International Workshop, IWOCA 2009, Revised Selected Papers
Pages36-47
Number of pages12
DOIs
StatePublished - 2009
Event20th International Workshop on Combinatorial Algorithms, IWOCA 2009 - Hradec nad Moravici, Czech Republic
Duration: 28 Jun 20092 Jul 2009

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume5874 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference20th International Workshop on Combinatorial Algorithms, IWOCA 2009
Country/TerritoryCzech Republic
CityHradec nad Moravici
Period28/06/092/07/09

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