TY - JOUR
T1 - Vulvar vestibulitis: A familial occurrence?
T2 - A familial occurrence?
AU - Bornstein, J.
AU - Ben-David, Y.
AU - Hornstein, L.
AU - Abramovici, H.
N1 - Copyright:
Copyright 2004 Elsevier B.V., All rights reserved.
PY - 1992/12/1
Y1 - 1992/12/1
N2 - In two sisters with severe dyspareunia, human papillomavirus (HPV) associated vulvar vestibulitis was diagnosed. One patient was treated by intramuscular injections of interferon-beta to a total dose of 45 million international units. The other by perineoplasty. The bioptic/surgical specimens revealed koilocytotic changes in the former and HPV-DNA (by dot blot hybridization) in the latter. Both patients resulted to be cured by therapies. The possibility of a familial occurrence of vestibulitis is discussed in addition to other pathogenetic hypotheses.
AB - In two sisters with severe dyspareunia, human papillomavirus (HPV) associated vulvar vestibulitis was diagnosed. One patient was treated by intramuscular injections of interferon-beta to a total dose of 45 million international units. The other by perineoplasty. The bioptic/surgical specimens revealed koilocytotic changes in the former and HPV-DNA (by dot blot hybridization) in the latter. Both patients resulted to be cured by therapies. The possibility of a familial occurrence of vestibulitis is discussed in addition to other pathogenetic hypotheses.
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VL - 10
SP - 167
EP - 169
JO - Cervix and the Lower Female Genital Tract
JF - Cervix and the Lower Female Genital Tract
IS - 3
ER -