Vitamin D antagonizes the expression of genes that are epigenetically regulated by Hepatitis C virus

R Zemel, N Rapaport, S Perez, Malka Esther Kitayner, Eteedal Morad, Marcela Karpuj, Amiram Ravid, Milana Frenkel-Morgenstern, Meital Gal-Tanamy, I. Haviv, Ran Tur-Kaspa

Research output: Contribution to conferenceAbstractpeer-review

Abstract

Increasing evidence show that Vitamin D has a pleiotropic effect, allowing it to target concurrently multiple epigenetic modifier enzymes. In particular: histone acetyl transferases (HATs), histone deacetylases (HDACs), histone methyl transferases (HMTs) and histone demethylases (HDMs). We have previously published that vitamin-D remarkably inhibits HCV production in hepatoma cells. Here, we aimed to study the effect of vitamin D on epigenetic alterations induced by HCV.
Original languageEnglish
Pages740A-741A
StatePublished - Oct 2016
Event67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases - Boston, MA, United States
Duration: 11 Nov 201615 Nov 2016

Conference

Conference67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases
Abbreviated title(AASLD)
Country/TerritoryUnited States
CityBoston, MA
Period11/11/1615/11/16

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