TY - JOUR
T1 - Vernal keratoconjunctivitis
T2 - The significance of immunoglobulin E levels in tears and serum
AU - Samra, Zemira
AU - Zavaro, Aron
AU - Barishak, Yomtov
AU - Sompolinsky, David
PY - 1984
Y1 - 1984
N2 - Vernal keratoconjunctivitis (VC) is an inflammatory disorder of the outer eye, probably of allergic etiology. The present study was performed on patients with a typical clinical appearance of VC and examined periodically for serum and tear IgE and albumin (HSA). The geometric mean of serum and tear IgE was 219 and 18 IU/ml, respectively, for the patients, but about 100 and less than 1 IU/ml for serum and tears of healthy controls and of parents of VC patients. A positive correlation between variations in tear IgE and tear HSA was observed, indicating that tear IgE levels have a significant influence on the intensity of the inflammatory process.
AB - Vernal keratoconjunctivitis (VC) is an inflammatory disorder of the outer eye, probably of allergic etiology. The present study was performed on patients with a typical clinical appearance of VC and examined periodically for serum and tear IgE and albumin (HSA). The geometric mean of serum and tear IgE was 219 and 18 IU/ml, respectively, for the patients, but about 100 and less than 1 IU/ml for serum and tears of healthy controls and of parents of VC patients. A positive correlation between variations in tear IgE and tear HSA was observed, indicating that tear IgE levels have a significant influence on the intensity of the inflammatory process.
UR - http://www.scopus.com/inward/record.url?scp=0021324713&partnerID=8YFLogxK
U2 - 10.1159/000233537
DO - 10.1159/000233537
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C2 - 6715062
AN - SCOPUS:0021324713
SN - 1018-2438
VL - 74
SP - 158
EP - 164
JO - International Archives of Allergy and Immunology
JF - International Archives of Allergy and Immunology
IS - 2
ER -