Value of antimalarial drugs in the treatment of lupus

Fadi Hassan, Mohammad E. Naffaa, Ziv Paz

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations


Antimalarial agents are now used as the standard of care for the treatment of systemic lupus erythematosus (SLE). The first documented use of antimalarial medications dates back to the sixteenth century. However, it was not until 1951 when Page, extrapolating from the observations he made during the Second World War, demonstrated clear success in treating 18 patients with cutaneous lupus. This was the beginning of a new era. Hydroxychloroquine came on the market in 1955 and, over the course of a few decades became the cornerstone of SLE treatment.

Original languageEnglish
Title of host publicationSystemic Lupus Erythematosus
Subtitle of host publicationBasic, Applied and Clinical Aspects
Number of pages5
ISBN (Electronic)9780128145517
ISBN (Print)9780128145524
StatePublished - 1 Jan 2020
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Inc. All rights reserved.


  • antimalarial
  • hydroxychloroquine
  • systemic lupus erythematosus


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