Use of nanobarcodes particles in bioassays.

R. Griffith Freeman, Paul A. Raju, Scott M. Norton, Ian D. Walton, Patrick C. Smith, Lin He, Michael J. Natan, Michael Y. Sha, Sharron G. Penn

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

We have developed striped metal nanoparticles, Nanobarcodes particles, which can act as encoded substrates in multiplexed assays. These particles are metallic, encodeable, machine-readable, durable, submicron-sized tags. The power of this technology is that the particles are intrinsically encoded by virtue of the difference in reflectivity of adjacent metal stripes. This chapter describes protocols for the attachment of biological molecules, and the subsequent use of the Nanobarcodes particles in bioassays.

Original languageEnglish
Pages (from-to)73-83
Number of pages11
JournalMethods in Molecular Biology
Volume303
StatePublished - 2005
Externally publishedYes

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