Trypsin inhibitor and maternal reunion increase plasma cholecystokinin in neonatal rats

Aron Weller; Eric S. Corp; Audrey Tyrka; Robert C. Ritter; Lynne Brenner; James Gibbs; Gerard P. Smith

doi:10.1016/0196-9781(92)90052-5

Trypsin inhibitor and maternal reunion increase plasma cholecystokinin in neonatal rats

Aron Weller, Eric S. Corp, Audrey Tyrka, Robert C. Ritter, Lynne Brenner, James Gibbs, Gerard P. Smith

Department of Psychology

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Intragastric soybean trypsin inhibitor increased plasma CCK bioactivity by 87% in nondeprived, 9-12-day-old rat pups. Reunion with the dam for 1 h after overnight maternal deprivation also increased plasma CCK significantly. These results demonstrate that CCK can be released from the small intestine of rats as early as postnatal day 9.

Original language	English
Pages (from-to)	939-941
Number of pages	3
Journal	Peptides
Volume	13
Issue number	5
DOIs	https://doi.org/10.1016/0196-9781(92)90052-5
State	Published - 1992

Bibliographical note

Funding Information:
The authors express their gratitude to Mrs. Jane Magnetti for processing the manuscript. Work in the Developmental Psychobiology Laboratory, Department of Psychology, Bar llan University was supported by the Charles E. Smith Family Foundation, the National Institute for Psychobiology in Israel, the Yigal Alon Fund, and a Bar Ilan University internal research fund to A.W. Work in the Bourne Laboratory was supported by MH40010 (E.S.C. and G.P.S.) and MH00149 (G.P.S.), and work in Dr. Ritter's laboratory was supported by NS20561.

Funding

The authors express their gratitude to Mrs. Jane Magnetti for processing the manuscript. Work in the Developmental Psychobiology Laboratory, Department of Psychology, Bar llan University was supported by the Charles E. Smith Family Foundation, the National Institute for Psychobiology in Israel, the Yigal Alon Fund, and a Bar Ilan University internal research fund to A.W. Work in the Bourne Laboratory was supported by MH40010 (E.S.C. and G.P.S.) and MH00149 (G.P.S.), and work in Dr. Ritter's laboratory was supported by NS20561.

Funders	Funder number
Bar Ilan University	MH40010, MH00149
Charles E. Smith Family Foundation
National Institute for Psychobiology in Israel
Yigal Alon Fund
National Institute of Neurological Disorders and Stroke	R01NS020561

Keywords

Bioassay of plasma CCK
Cholecystokinin (CCK) release
Gut hormones
Meternal deprivation
Ontogeny of feeding
Peptides
Satiety
Small intestinal CCK
Trypsin inhibitor

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10.1016/0196-9781(92)90052-5

Cite this

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title = "Trypsin inhibitor and maternal reunion increase plasma cholecystokinin in neonatal rats",

abstract = "Intragastric soybean trypsin inhibitor increased plasma CCK bioactivity by 87% in nondeprived, 9-12-day-old rat pups. Reunion with the dam for 1 h after overnight maternal deprivation also increased plasma CCK significantly. These results demonstrate that CCK can be released from the small intestine of rats as early as postnatal day 9.",

keywords = "Bioassay of plasma CCK, Cholecystokinin (CCK) release, Gut hormones, Meternal deprivation, Ontogeny of feeding, Peptides, Satiety, Small intestinal CCK, Trypsin inhibitor",

author = "Aron Weller and Corp, {Eric S.} and Audrey Tyrka and Ritter, {Robert C.} and Lynne Brenner and James Gibbs and Smith, {Gerard P.}",

note = "Funding Information: The authors express their gratitude to Mrs. Jane Magnetti for processing the manuscript. Work in the Developmental Psychobiology Laboratory, Department of Psychology, Bar llan University was supported by the Charles E. Smith Family Foundation, the National Institute for Psychobiology in Israel, the Yigal Alon Fund, and a Bar Ilan University internal research fund to A.W. Work in the Bourne Laboratory was supported by MH40010 (E.S.C. and G.P.S.) and MH00149 (G.P.S.), and work in Dr. Ritter's laboratory was supported by NS20561.",

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doi = "10.1016/0196-9781(92)90052-5",

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AU - Weller, Aron

AU - Corp, Eric S.

AU - Tyrka, Audrey

AU - Ritter, Robert C.

AU - Brenner, Lynne

AU - Gibbs, James

AU - Smith, Gerard P.

N1 - Funding Information: The authors express their gratitude to Mrs. Jane Magnetti for processing the manuscript. Work in the Developmental Psychobiology Laboratory, Department of Psychology, Bar llan University was supported by the Charles E. Smith Family Foundation, the National Institute for Psychobiology in Israel, the Yigal Alon Fund, and a Bar Ilan University internal research fund to A.W. Work in the Bourne Laboratory was supported by MH40010 (E.S.C. and G.P.S.) and MH00149 (G.P.S.), and work in Dr. Ritter's laboratory was supported by NS20561.

PY - 1992

Y1 - 1992

N2 - Intragastric soybean trypsin inhibitor increased plasma CCK bioactivity by 87% in nondeprived, 9-12-day-old rat pups. Reunion with the dam for 1 h after overnight maternal deprivation also increased plasma CCK significantly. These results demonstrate that CCK can be released from the small intestine of rats as early as postnatal day 9.

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KW - Cholecystokinin (CCK) release

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KW - Meternal deprivation

KW - Ontogeny of feeding

KW - Peptides

KW - Satiety

KW - Small intestinal CCK

KW - Trypsin inhibitor

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Trypsin inhibitor and maternal reunion increase plasma cholecystokinin in neonatal rats

Abstract

Bibliographical note

Funding

Keywords

Access to Document

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