Abstract
Recently, nanoparticles have emerged as promising contrast agents for various imaging applications. In this paper, we present the synthesis and characterization of a novel hybrid nano-struc-ture, consisting of an iron oxide@gold nanoparticle, labeled with technetium-99m, for trimodal SPECT/CT/MRI imaging. The particles showed efficient capabilities as CT/MRI imaging agent and high radiochemical yield, indicating a potential single hybrid material for multimodal SPECT/CT/MRI.
| Original language | English |
|---|---|
| Pages (from-to) | 291-294 |
| Number of pages | 4 |
| Journal | Chemistry Letters |
| Volume | 48 |
| Issue number | 3 |
| DOIs | |
| State | Published - 2019 |
Bibliographical note
Publisher Copyright:© 2019 The Chemical Society of Japan.
Funding
This project received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement #761031. This publication reflects only the author’s views and the European Union is not liable for any use that may be made of the information contained herein. We thank the Ministry of Science and Technology, Israel for T.D.’s scholarship, and partial support by Stavros Niarchos Foundation Industrial Scholarships, enhancing research in Greece. We thank Dr. Penelope Bouziotis, Research Director at the Radiochemical Studies Lab, for the radiolabeling studies at the National Center of Scientific Research “Demokritos”; and Chen Zror-Azankot for assistance with scheme creation.
| Funders | Funder number |
|---|---|
| Horizon 2020 Framework Programme | |
| Stavros Niarchos Foundation | |
| Centre National de la Recherche Scientifique | |
| Ministry of science and technology, Israel | |
| Horizon 2020 | 761031 |
Keywords
- Core/shell nanoparticles
- Multimodal imaging
- Nanoparticle contrast agents