Abstract
The structure of a new withanolide type isolated from Trechonaetes laciniata, having a hemiacetal ring system and a 5-member ring lactone has been elucidated by X-ray analysis as (23R)-5β,6β-epoxy-12β,17β-dihydroxy-1-oxo-12,22-hemiacetal-ergosta-2,24-dien-23,26-olide (trechonolide A). A second compound (trechonolide B) having at C-12 a β-methoxy group, has also been isolated and assumed to be an artifact since, by heating trechonolide A in methanol with a trace of acid, the methoxy derivative was produced.
| Original language | English |
|---|---|
| Pages (from-to) | 1791-1795 |
| Number of pages | 5 |
| Journal | Phytochemistry |
| Volume | 26 |
| Issue number | 6 |
| DOIs | |
| State | Published - 1987 |
Keywords
- Solanaceae
- Trechonaetes laciniata
- X-ray structure
- steroidal lactones
- trechonolide A
- trichloroacetyl isocyanate derivatives.
- withanolides