TY - JOUR
T1 - Transplacental passage of insulin (II)
AU - Ben-Shlomo, I.
AU - Dor, J.
AU - Zohar, S.
AU - Mashiach, S.
PY - 1991/1/17
Y1 - 1991/1/17
N2 - To the Editor: Menon et al. (Aug. 2 issue)1 make the interesting observation that animal insulin, mainly in the form of insulin-antibody complexes, can be detected in the cord serum of some infants born to mothers with insulin-dependent diabetes mellitus treated with animal insulin. The authors conclude that the higher rate of macrosomia in infants of such mothers is partly due to the stimulatory effect of the transplacentally transferred insulin.1 We disagree with this conclusion. If the animal insulin transferred from the mother to the fetus contributed to fetal macrosomia, one would expect a lower rate of macrosomia in the.
AB - To the Editor: Menon et al. (Aug. 2 issue)1 make the interesting observation that animal insulin, mainly in the form of insulin-antibody complexes, can be detected in the cord serum of some infants born to mothers with insulin-dependent diabetes mellitus treated with animal insulin. The authors conclude that the higher rate of macrosomia in infants of such mothers is partly due to the stimulatory effect of the transplacentally transferred insulin.1 We disagree with this conclusion. If the animal insulin transferred from the mother to the fetus contributed to fetal macrosomia, one would expect a lower rate of macrosomia in the.
UR - http://www.scopus.com/inward/record.url?scp=0025966325&partnerID=8YFLogxK
U2 - 10.1056/nejm199101173240314
DO - 10.1056/nejm199101173240314
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C2 - 1984201
AN - SCOPUS:0025966324
SN - 0028-4793
VL - 324
SP - 198
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 3
ER -