Tracking bio-molecules in live cells using quantum dots

Yun Pei Chang, Fabien Pinaud, Joshua Antelman, Shimon Weiss

Research output: Contribution to journalReview articlepeer-review

107 Scopus citations


Single particle tracking (SPT) techniques were developed to explore bio-molecules dynamics in live cells at single molecule sensitivity and nanometer spatial resolution. Recent developments in quantum dots (Qdots) surface coating and bio-conjugation schemes have made them most suitable probes for live cell applications. Here we review recent advancements in using quantum dots as SPT probes for live cell experiments.

Original languageEnglish
Pages (from-to)287-298
Number of pages12
JournalJournal of Biophotonics
Issue number4
StatePublished - 2008
Externally publishedYes


  • Live cell tracking
  • Quantum dots
  • Single particle tracking
  • Super-resolution


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