Total synthesis of (11R, 12S)-diHETE

Agnès Gigou, Jean Pierre Beaucourt, Jean Paul Lellouche, René Gree

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


The first total synthesis of (11R, 12S) diHETE is reported. The key step is the highly chemio- and stereoselective osmylation of a double bond in a trienyne system selectively complexed by an Fe(CO)3 group.

Original languageEnglish
Pages (from-to)635-638
Number of pages4
JournalTetrahedron Letters
Issue number5
StatePublished - 28 Jan 1991
Externally publishedYes


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