Torsades de pointes and QT prolongation due to a combination of loratadine and amiodarone

Shaul Atar; Nahum A. Freedberg; Dante Antonelli; Tiberio Rosenfeld

doi:10.1046/j.1460-9592.2003.00137.x

Torsades de pointes and QT prolongation due to a combination of loratadine and amiodarone

Shaul Atar, Nahum A. Freedberg, Dante Antonelli, Tiberio Rosenfeld

Emek Medical Center

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Torsades de pointes (TdP) has not been previously reported with loratadine. A 73-year old woman on chronic treatment with amiodarone for atrial fibrillation received loratadine and presented with syncope and multiple episodes of TdP. We suggest that QT interval should be monitored whenever loratadine is co-administered with drugs that may potentially prolong QT.

Original language	English
Pages (from-to)	785-786
Number of pages	2
Journal	PACE - Pacing and Clinical Electrophysiology
Volume	26
Issue number	3
DOIs	https://doi.org/10.1046/j.1460-9592.2003.00137.x
State	Published - 1 Mar 2003
Externally published	Yes

Keywords

Amiodarone
Loratadine
QT dispersion
QT interval
Torsades de pointes

Access to Document

10.1046/j.1460-9592.2003.00137.x

Cite this

@article{b906224274ad4fc290567769acd9ba70,

title = "Torsades de pointes and QT prolongation due to a combination of loratadine and amiodarone",

abstract = "Torsades de pointes (TdP) has not been previously reported with loratadine. A 73-year old woman on chronic treatment with amiodarone for atrial fibrillation received loratadine and presented with syncope and multiple episodes of TdP. We suggest that QT interval should be monitored whenever loratadine is co-administered with drugs that may potentially prolong QT.",

keywords = "Amiodarone, Loratadine, QT dispersion, QT interval, Torsades de pointes",

author = "Shaul Atar and Freedberg, {Nahum A.} and Dante Antonelli and Tiberio Rosenfeld",

year = "2003",

month = mar,

day = "1",

doi = "10.1046/j.1460-9592.2003.00137.x",

language = "אנגלית",

volume = "26",

pages = "785--786",

journal = "PACE - Pacing and Clinical Electrophysiology",

issn = "0147-8389",

publisher = "John Wiley and Sons Inc.",

number = "3",

}

TY - JOUR

T1 - Torsades de pointes and QT prolongation due to a combination of loratadine and amiodarone

AU - Atar, Shaul

AU - Freedberg, Nahum A.

AU - Antonelli, Dante

AU - Rosenfeld, Tiberio

PY - 2003/3/1

Y1 - 2003/3/1

N2 - Torsades de pointes (TdP) has not been previously reported with loratadine. A 73-year old woman on chronic treatment with amiodarone for atrial fibrillation received loratadine and presented with syncope and multiple episodes of TdP. We suggest that QT interval should be monitored whenever loratadine is co-administered with drugs that may potentially prolong QT.

AB - Torsades de pointes (TdP) has not been previously reported with loratadine. A 73-year old woman on chronic treatment with amiodarone for atrial fibrillation received loratadine and presented with syncope and multiple episodes of TdP. We suggest that QT interval should be monitored whenever loratadine is co-administered with drugs that may potentially prolong QT.

KW - Amiodarone

KW - Loratadine

KW - QT dispersion

KW - QT interval

KW - Torsades de pointes

UR - http://www.scopus.com/inward/record.url?scp=0037354632&partnerID=8YFLogxK

U2 - 10.1046/j.1460-9592.2003.00137.x

DO - 10.1046/j.1460-9592.2003.00137.x

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 12698686

AN - SCOPUS:0037354632

SN - 0147-8389

VL - 26

SP - 785

EP - 786

JO - PACE - Pacing and Clinical Electrophysiology

JF - PACE - Pacing and Clinical Electrophysiology

IS - 3

ER -

Torsades de pointes and QT prolongation due to a combination of loratadine and amiodarone

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this