Tone Stimulus Detection For Rats Using RRAM-Based Local Field Potential Monitoring

Caterina Sbandati; Spyros Stathopoulos; Patrick Foster; Noam D. Peer; Alexantrou Serb; Shiwei Wang; Dana Cohen; Themis Prodromakis

doi:10.1109/BioCAS58349.2023.10388917

Tone Stimulus Detection For Rats Using RRAM-Based Local Field Potential Monitoring

Caterina Sbandati, Spyros Stathopoulos, Patrick Foster, Noam D. Peer, Alexantrou Serb, Shiwei Wang, Dana Cohen, Themis Prodromakis

University of Edinburgh

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

The comprehension of brain activity presents significant challenges in the field of neuroscience. Contrary to spikes, Local Field Potentials (LFPs) present improved stability acquisition in chronic implant scenarios and potential reductions in sampling and processing rates. While existing electrophysiology acquisition systems focus predominantly on spike detection and sorting, there is a lack of real-time tools for exploiting LFPs. To address this gap, we present a Resistive-RAM (RRAM) based approach to process LFP traces. Our method follows an improved Memristive Integrating Sensor (MIS) protocol to effectively detect LFP events recorded from the deep-brain of an awake rat, while externally stimulated by a tone. Experimental results demonstrate the feasibility of real-time neural activity processing, offering insights into detecting meaningful external stimuli and facilitating efficient neural state estimation.

Original language	English
Title of host publication	BioCAS 2023 - 2023 IEEE Biomedical Circuits and Systems Conference, Conference Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9798350300260
DOIs	https://doi.org/10.1109/BioCAS58349.2023.10388917
State	Published - 2023
Event	2023 IEEE Biomedical Circuits and Systems Conference, BioCAS 2023 - Toronto, Canada Duration: 19 Oct 2023 → 21 Oct 2023

Publication series

Name	BioCAS 2023 - 2023 IEEE Biomedical Circuits and Systems Conference, Conference Proceedings

Conference

Conference	2023 IEEE Biomedical Circuits and Systems Conference, BioCAS 2023
Country/Territory	Canada
City	Toronto
Period	19/10/23 → 21/10/23

Bibliographical note

Publisher Copyright:
© 2023 IEEE.

Funding

This work has been supported by the UK Engineering and Physical Sciences Research Council grant EP/R024642/1 (FORTE) and the EU commission H2020 programme no. 824165 (SYNCH).

Funders	Funder number
EU commission H2020	824165
Engineering and Physical Sciences Research Council	EP/R024642/1
Forskningsrådet om Hälsa, Arbetsliv och Välfärd

Keywords

RRAM
bio-signal processing
edge processing
local field potential (LFP)
memristor
real-time detection

Access to Document

10.1109/BioCAS58349.2023.10388917

Cite this

Sbandati, C., Stathopoulos, S., Foster, P., Peer, N. D., Serb, A., Wang, S., Cohen, D., & Prodromakis, T. (2023). Tone Stimulus Detection For Rats Using RRAM-Based Local Field Potential Monitoring. In BioCAS 2023 - 2023 IEEE Biomedical Circuits and Systems Conference, Conference Proceedings (BioCAS 2023 - 2023 IEEE Biomedical Circuits and Systems Conference, Conference Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BioCAS58349.2023.10388917

Sbandati, Caterina ; Stathopoulos, Spyros ; Foster, Patrick et al. / Tone Stimulus Detection For Rats Using RRAM-Based Local Field Potential Monitoring. BioCAS 2023 - 2023 IEEE Biomedical Circuits and Systems Conference, Conference Proceedings. Institute of Electrical and Electronics Engineers Inc., 2023. (BioCAS 2023 - 2023 IEEE Biomedical Circuits and Systems Conference, Conference Proceedings).

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abstract = "The comprehension of brain activity presents significant challenges in the field of neuroscience. Contrary to spikes, Local Field Potentials (LFPs) present improved stability acquisition in chronic implant scenarios and potential reductions in sampling and processing rates. While existing electrophysiology acquisition systems focus predominantly on spike detection and sorting, there is a lack of real-time tools for exploiting LFPs. To address this gap, we present a Resistive-RAM (RRAM) based approach to process LFP traces. Our method follows an improved Memristive Integrating Sensor (MIS) protocol to effectively detect LFP events recorded from the deep-brain of an awake rat, while externally stimulated by a tone. Experimental results demonstrate the feasibility of real-time neural activity processing, offering insights into detecting meaningful external stimuli and facilitating efficient neural state estimation.",

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author = "Caterina Sbandati and Spyros Stathopoulos and Patrick Foster and Peer, {Noam D.} and Alexantrou Serb and Shiwei Wang and Dana Cohen and Themis Prodromakis",

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Sbandati, C, Stathopoulos, S, Foster, P, Peer, ND, Serb, A, Wang, S, Cohen, D & Prodromakis, T 2023, Tone Stimulus Detection For Rats Using RRAM-Based Local Field Potential Monitoring. in BioCAS 2023 - 2023 IEEE Biomedical Circuits and Systems Conference, Conference Proceedings. BioCAS 2023 - 2023 IEEE Biomedical Circuits and Systems Conference, Conference Proceedings, Institute of Electrical and Electronics Engineers Inc., 2023 IEEE Biomedical Circuits and Systems Conference, BioCAS 2023, Toronto, Canada, 19/10/23. https://doi.org/10.1109/BioCAS58349.2023.10388917

Tone Stimulus Detection For Rats Using RRAM-Based Local Field Potential Monitoring. / Sbandati, Caterina; Stathopoulos, Spyros; Foster, Patrick et al.
BioCAS 2023 - 2023 IEEE Biomedical Circuits and Systems Conference, Conference Proceedings. Institute of Electrical and Electronics Engineers Inc., 2023. (BioCAS 2023 - 2023 IEEE Biomedical Circuits and Systems Conference, Conference Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Prodromakis, Themis

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Sbandati C, Stathopoulos S, Foster P, Peer ND, Serb A, Wang S et al. Tone Stimulus Detection For Rats Using RRAM-Based Local Field Potential Monitoring. In BioCAS 2023 - 2023 IEEE Biomedical Circuits and Systems Conference, Conference Proceedings. Institute of Electrical and Electronics Engineers Inc. 2023. (BioCAS 2023 - 2023 IEEE Biomedical Circuits and Systems Conference, Conference Proceedings). doi: 10.1109/BioCAS58349.2023.10388917

Tone Stimulus Detection For Rats Using RRAM-Based Local Field Potential Monitoring

Abstract

Publication series

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Bibliographical note

Funding

Keywords

Access to Document

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