Time-resolved FRET detection of subtle temperature-induced conformational biases in ensembles of α-synuclein molecules

Keyphrases

• Temperature Effect 100%
• Alpha-synuclein (α-syn) 100%
• Time-resolved FRET 100%
• Conformity Bias 100%
• Diffusion Coefficient 66%
• Polypeptide 66%
• Disordered State 66%
• High Temperature 33%
• N-terminal Domain 33%
• Structural Constraints 33%
• Temperature Range 33%
• Parkinson's Disease 33%
• Time-resolved 33%
• Misfolding 33%
• Fast Fluctuations 33%
• End-to-end Distance 33%
• Short Segment 33%
• Intrinsically Disordered Proteins 33%
• Weak Effect 33%
• Two-segment 33%
• Excitation Energy Transfer 33%
• Excluded Volume Effect 33%
• Chain Segment 33%
• Temperature-induced Unfolding 33%
• Cooperative Transition 33%
• NAC Domain 33%

Biochemistry, Genetics and Molecular Biology

• N-Terminus 100%
• Fluorescence Resonance Energy Transfer 100%
• Diffusion Coefficient 100%
• Temperature Dependence 100%
• Synuclein 100%
• Intrinsically Disordered Protein 50%
• Energy Transfer 50%