Time-gated biological imaging by use of colloidal quantum dots

M. Dahan, T. Laurence, F. Pinaud, D. S. Chemla, A. P. Alivisatos, M. Sauer, S. Weiss

Research output: Contribution to journalArticlepeer-review

312 Scopus citations


The long (but not too long) fluorescence lifetime of CdSe semiconductor quantum dots was exploited to enhance fluorescence biological imaging contrast and sensitivity by time-gated detection. Significant and selective reduction of the autofluorescence contribution to the overall image was achieved, and enhancement of the signal-to-background ratio by more than an order of magnitude was demonstrated.

Original languageEnglish
Pages (from-to)825-827
Number of pages3
JournalOptics Letters
Issue number11
StatePublished - 1 Jun 2001
Externally publishedYes


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