Theory and evaluation of single-molecule signals

Eli Barkai, Frank L.H. Brown, Michel Orrit, Haw Yang

Research output: Book/ReportBookpeer-review

45 Scopus citations


This book reviews recently developed theoretical and numerical approaches to deal with optical and mechanical signals from individual molecules. The character of data generated by single molecules, and more generally by single nano-objects, qualitatively differs from those obtained in conventional experiments on large ensembles of molecules. Fluctuations, randomness and irreproducibility are central to single-molecule measurements, and the specific methods required to extract reliable and statistically relevant information from them are presented here. With contributions mainly from participants of the “Theory, Modeling and Evaluation of Single-Molecule Measurements” workshop held in Leiden, the Netherlands, on April 16-20, 2007, this book is an authoritative compendium on the subject.

Original languageEnglish
PublisherWorld Scientific Publishing Co.
Number of pages399
ISBN (Electronic)9789812793492
ISBN (Print)9812793488, 9789812793485
StatePublished - 1 Jan 2008

Bibliographical note

Publisher Copyright:
© 2008 by World Scientific Publishing Co. Pte. Ltd. All rights reserved.


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