The yield of lleoscopy: Does indication matter?

Amir Mari, Tawfik Khoury, Mahmud Mahamid, Shorbaji Akram, Yael Kopelman, Fadi Abu Baker

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Background: While the routine performance of terminal ileum (Tl) intubation during colonoscopy procedures is perceived to have a low yield, its utility during colonoscopies performed for specific indications have not been well studied. Objectives: To assess the diagnostic yield of an indication-based ileoscopy in real-life practice. Methods: The authors reviewed endoscopic reports of patients who underwent colonoscopies over an 8-year period (2011-2018) and had routine ileoscopy during these procedures. Demographic data, indications for colonoscopy, and endoscopic findings were documented. Diagnostic yield and odds ratio for Tl findings were calculated. Results: Over 30,000 colonoscopy reports performed during the study period were reviewed. Ilesocopy was performed in 1800 patients, 216 patients had findings in the Tl (ileitis or ulcers). Tl findings were more prevalent in younger ages (38.3 ± 17.6 vs. 43.6 ± 20, P < 0.05). The greatest yield of ileoscopy was evident when performed for the evaluation of chronic abdominal pain and diarrhea (14.4% vs. 9.3%, odds ratio [OR] 1.62, P< 0.05). Positive fecal occult blood test (FOBT) (OR 0.1,95% confidence interval [95%CI] 0.02-0.5, P = 0.005) and constipation (OR 0.44, 95%CI 0.2-0.9, P = 0.04) were negatively associated with Tl findings. Conclusions: Ileoscopy may have the greatest utility in evaluating suspected inflammatory bowel disease (IBD) patients, but may not add value to the evaluation of constipation and positive FOBT.

Original languageEnglish
Pages (from-to)684-687
Number of pages4
JournalIsrael Medical Association Journal
Issue number11
StatePublished - Nov 2020

Bibliographical note

Publisher Copyright:
© 2020 Israel Medical Association. All rights reserved.


  • Colonoscopy
  • Fecal occult blood test (FOBT)
  • Ileoscopy
  • Inflammatory bowel disease (IBD)
  • Terminal ileum (Tl)


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