The use of oral radiographic contrast agents in the management of hyperthyroidism

J. C. Fontanilla, A. B. Schneider, D. H. Sarne

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations


Oral iodinated radiographic contrast agents such as ipodate and iopanoic acid form an important part of the armamentarium used to treat hyperthyroidism. They rapidly and dramatically reduce serum triiodothyronine (T3) levels by inhibiting conversion of thyroxine (T4) to T3 in the periphery and by blocking secretion from the thyroid. Potential risks from the large iodine load resulting from their use limit their widespread applicability. In addition, they are ineffective when used alone on a long-term basis. However, these agents may be especially useful in treating thyrotoxic patients preoperatively, in neonatal Graves' disease, in massive levothyroxine ingestion, and when other conventional antithyroid drugs are unsuccessful or contraindicated.

Original languageEnglish
Pages (from-to)561-567
Number of pages7
Issue number6
StatePublished - 2001
Externally publishedYes


Dive into the research topics of 'The use of oral radiographic contrast agents in the management of hyperthyroidism'. Together they form a unique fingerprint.

Cite this