The synthesis of the vitamers of biotin

Abraham Nudelman, Ayelet Nudelman, Dana Marcovici-Mizrahi, Dennis Flint

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


An efficient synthetic pathway for the preparation of the vitamers of biotin which provides easy access to optically pure KAPA as well as diastereomeric mixtures of DAPA, DTB, and analogs thereof has been developed.

Original languageEnglish
Pages (from-to)157-168
Number of pages12
JournalBioorganic Chemistry
Issue number3
StatePublished - Oct 1998


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