The synthesis of ribosomal-type rna by isolated rat liver mitochondria

S. Fukamachi; B. Bartoov; R. S. Mitra; K. B. Freeman

doi:10.1016/0006-291X(70)90981-2

The synthesis of ribosomal-type rna by isolated rat liver mitochondria

S. Fukamachi, B. Bartoov, R. S. Mitra, K. B. Freeman

McMaster University

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Isolated rat liver mitochondria have been shown to synthesize RNA which has an electrophoretic mobility of "21S" and "12S" on agarose-acrylamide gels. The synthesis of these RNA species was inhibited by ethidium bromide. From these observations it is suggested that mammalian mitochondrial DNA codes for mitochondrial ribosomal-type RNA.

Original language	English
Pages (from-to)	852-857
Number of pages	6
Journal	Biochemical and Biophysical Research Communications
Volume	40
Issue number	4
DOIs	https://doi.org/10.1016/0006-291X(70)90981-2
State	Published - 24 Aug 1970
Externally published	Yes

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10.1016/0006-291X(70)90981-2

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AB - Isolated rat liver mitochondria have been shown to synthesize RNA which has an electrophoretic mobility of "21S" and "12S" on agarose-acrylamide gels. The synthesis of these RNA species was inhibited by ethidium bromide. From these observations it is suggested that mammalian mitochondrial DNA codes for mitochondrial ribosomal-type RNA.

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The synthesis of ribosomal-type rna by isolated rat liver mitochondria

Abstract

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