Abstract
Introduction: Troponin T and I are located in the myocardium. Monitoring blood Troponin levels is advantageous in evaluating unstable angina over measuring CPK-MB, previously serving as a golden standard for urgent evaluation of myocardial infarct. Aim: To measure blood troponin T levels in hemodialysis patients without severe cardiovascular events, following its distribution according to various risk factors. Methods: Sera were collected from 68 hemodialysis (HD) patients before starting dialysis sessions and compared to 10 age- and gender-matched healthy volunteers (NC). Troponin T levels were measured using Troponin T STAT Elecsys-Roche kits. Results: Blood Troponin T levels were significantly higher in HD patients compared to NC (0.1260.016 vs. 0.0050 ng/dL, respectively P=0.026). HD patients with ischemic heart disease (IHD) showed significantly higher levels of Troponin T, compared to HD patients without IHD (0.170.036 vs. 0.0810.015 ng/dL, respectively P=0.012). Diabetic (DM) HD patients showed higher levels of Troponin T, compared to non-DM HD patients (0.1680.034 vs. 0.0680.012 ng/dL, respectively P=0.002). Conclusion: Troponin T may efficiently serve as a diagnostic, monitoring and prognostic parameter in HD patients.
| Original language | Hebrew |
|---|---|
| Pages (from-to) | 875-878 |
| Number of pages | 4 |
| Journal | Harefuah |
| Volume | 145 |
| Issue number | 12 SPEC. ISS. |
| State | Published - Dec 2006 |
| Externally published | Yes |
Keywords
- Diabetes mellitus
- Hemodialysis
- Ischemic heart disease
- Troponin
