The reaction of LiAlH4/HMPA with oximes: Mechanism and synthetic applications

Natarajan Balachander, Shin Shin Hang, Chaim N. Sukenik

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Three aspects of the reaction of LiAlH4 in HMPA with oximes have been studied: the mechanism of the conversion of ketoximes into ketones, application of this reaction to the selective reduction of enones to ketones via the ene-oxime, and the conversion of aldoximes to either nitriles or aldehydes as a function of substrate structure.

Original languageEnglish
Pages (from-to)4849-4852
Number of pages4
JournalTetrahedron Letters
Volume27
Issue number40
DOIs
StatePublished - 1986
Externally publishedYes

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