The Prominent Motif of the Leaving Group in Chemical and Biological Processes of Phosphonoesters: Understanding the Behavior of V-type Nerve Agents

Keyphrases

• Biological Processes 100%
• Hydroxide 100%
• Chemical Processes 100%
• Leaving Group 100%
• V-type Nerve Agents 100%
• Fluoride 66%
• Scission 33%
• Transition State 33%
• Amines 33%
• DFT Calculations 33%
• Methanol 33%
• Nucleophile 33%
• Product Distribution 33%
• Nerve Agents 33%
• Biochemical Processes 33%
• Reaction Products 33%
• DFT Study 33%
• Methoxide 33%
• Bond Cleavage 33%
• Decontamination 33%
• Solvolysis 33%
• Solvolysis Reaction 33%
• Reaction Rate Distribution 33%
• Toxicity Persistence 33%
• State Energy 33%
• Phosphonylation 33%

Chemistry

• Nerve Agent 100%
• Density Functional Theory 50%
• Solvolysis 50%
• Transition State 25%
• Toxic 25%
• Methanol 25%
• Product Distribution 25%
• pKa 25%
• Methoxide 25%
• Decontamination 25%
• Phosphonylation 25%
• Nucleophile 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Nerve Gas 100%
• Nucleophile 33%
• Bond Cleavage 33%
• Methanol 33%
• VX (Nerve Agent) 33%