The presence of erythropoietin receptors in the human peripheral nervous system

Kamal Hassan, B. Gross, W. Simri, I. Rubinchik, H. Cohen, J. Jacobi, S. M. Shasha, B. Kristal

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Erythropoietin (EPO) is a well-known hematopoietic factor and a major determinant of tissue oxygenation. EPO receptors have been identified on a wide variety of non-erythroid cell types including human central nervous system and peripheral nervous system of animal models. The presence or function of EPO receptors in human peripheral nervous system is unknown. By examining nerve segments from radicular and autonomic nerves using immunohistochemical methods, we demonstrated the presence of EPO receptors on myelin sheath of radicular nerves in the human peripheral nervous system.

Original languageEnglish
Pages (from-to)127-129
Number of pages3
JournalClinical Nephrology
Issue number2
StatePublished - Feb 2004
Externally publishedYes


  • Erythropoietin receptors
  • Human peripheral nervous system
  • Nonhematopoieti functions
  • Peripheral polyneuropathy


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