The preparation of magnetic proteinaceous microspheres using the sonochemical method

S. Avivi, I. Felner, I. Novik, A. Gedanken

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Using high-intensity ultrasound, we have developed a method for the synthesis of magnetic microspheres. The microspheres are composed of iron oxide-filled and coated globular bovine serum albumin (BSA). The magnetic microspheres are prepared from BSA and iron pentacarbonyl, or from BSA and iron acetate. Transmission electron microscopy and scanning electron microscopy show spherical particles. The particle size distributions are gaussian, with a mean diameter of a few micrometers. Using chemical analysis, it was found that the total percentage of iron oxide in the microspheres is between 39% and 42%. Mössbauer measurements were also performed.

Original languageEnglish
Pages (from-to)123-129
Number of pages7
JournalBiochimica et Biophysica Acta - General Subjects
Volume1527
Issue number3
DOIs
StatePublished - 15 Aug 2001

Bibliographical note

Funding Information:
A. Gedanken thanks the German Ministry of Education and Research through the Deutsche–Israeli Program (DIP) for its financial support.

Funding

A. Gedanken thanks the German Ministry of Education and Research through the Deutsche–Israeli Program (DIP) for its financial support.

FundersFunder number
Deutsche–Israeli Program
Bundesministerium für Bildung und Forschung

    Keywords

    • Amorphous iron oxide
    • Magnetic nanoparticles
    • Nanoparticles
    • Proteinaceous microspheres
    • Sonochemistry

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