Abstract
Using high-intensity ultrasound, we have developed a method for the synthesis of magnetic microspheres. The microspheres are composed of iron oxide-filled and coated globular bovine serum albumin (BSA). The magnetic microspheres are prepared from BSA and iron pentacarbonyl, or from BSA and iron acetate. Transmission electron microscopy and scanning electron microscopy show spherical particles. The particle size distributions are gaussian, with a mean diameter of a few micrometers. Using chemical analysis, it was found that the total percentage of iron oxide in the microspheres is between 39% and 42%. Mössbauer measurements were also performed.
Original language | English |
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Pages (from-to) | 123-129 |
Number of pages | 7 |
Journal | Biochimica et Biophysica Acta - General Subjects |
Volume | 1527 |
Issue number | 3 |
DOIs | |
State | Published - 15 Aug 2001 |
Bibliographical note
Funding Information:A. Gedanken thanks the German Ministry of Education and Research through the Deutsche–Israeli Program (DIP) for its financial support.
Funding
A. Gedanken thanks the German Ministry of Education and Research through the Deutsche–Israeli Program (DIP) for its financial support.
Funders | Funder number |
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Deutsche–Israeli Program | |
Bundesministerium für Bildung und Forschung |
Keywords
- Amorphous iron oxide
- Magnetic nanoparticles
- Nanoparticles
- Proteinaceous microspheres
- Sonochemistry