The neurocognitive outcome of IUGR children born to mothers with and without preeclampsia

Y. Leitner, S. Harel, R. Geva, R. Eshel, A. Yaffo, A. Many

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Objective: To examine long-term behavioral and neurodevelopmental outcome of children born growth restricted and exposed to hypertension in utero at 9 years of age. Methods: Somatic growth and neurocognitive outcomes were evaluated at age 910 years of age in 42 children born with intra uterine growth restriction (IUGR) after pregnancies complicated by hypertensive disorder (17 with maternal preeclampsia and 25 after gestational hypertension). This study group was compared to a control group of 78 IUGR children born after normotensive pregnancy. Results: Only weight was found to be significantly lower in the hypertensive-IUGR group, versus the normotensive IUGR children. No significant differences were found in any of the neurocognitive parameters including IQ, school achievements, and neurodevelopmental score at age 910 years. Conclusion: IUGR is a well known risk factor for later cognitive difficulties but maternal hypertensive disorder does not seem to add significantly to this risk.

Original languageEnglish
Pages (from-to)2206-2208
Number of pages3
JournalJournal of Maternal-Fetal and Neonatal Medicine
Issue number11
StatePublished - Nov 2012
Externally publishedYes


  • IUGR
  • Neurodevelopmental outcome
  • Preeclampsia


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