The MATRICS consensus cognitive battery: What We know 6 years later

Michael F. Green, Josette G. Harris, Keith H. Nuechterlein

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations

Abstract

After substantial use in the testing ground of multisite clinical trials, the MCCB has demonstrated impressive psychometrics. It has shown sensitivity to improvement from interventions, most notably for cognitive training interventions so far. We do not believe that the MCCB is inherently more sensitive to training than to pharmacological interventions; that pattern most likely reflects the state of that field, in which we have few validated cognition-enhancing drugs. TheMCCB also tracks with key biomarkers, which is an important feature as efforts are made to apply experimental medicine principles, such as target engagement, to psychiatric treatment trials.

Original languageEnglish
Pages (from-to)1151-1154
Number of pages4
JournalAmerican Journal of Psychiatry
Volume171
Issue number11
DOIs
StatePublished - 1 Nov 2014
Externally publishedYes

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