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The MATRICS consensus Cognitive battery (MCCB): Co-norming and standardization in Spain

  • R. Rodriguez-Jimenez
  • , A. Bagney
  • , C. Garcia-Navarro
  • , A. I. Aparicio
  • , R. Lopez-Anton
  • , M. Moreno-Ortega
  • , M. A. Jimenez-Arriero
  • , J. L. Santos
  • , A. Lobo
  • , R. S. Kern
  • , M. F. Green
  • , K. H. Nuechterlein
  • , T. Palomo
  • Hospital Universitario 12 de Octubre
  • Centro de Investigación Biomédica en Red
  • Hospital General Virgen de la Luz
  • Hospital Clinico Universitario "Lozano Blesa" de Zaragoza
  • University of California at Los Angeles
  • Department of Veterans Affairs

Research output: Contribution to journalArticlepeer-review

68 Scopus citations

Abstract

The MATRICS Consensus Cognitive Battery (MCCB), developed by the National Institute of Mental Health (NIMH) Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) initiative, has been recommended as the standard battery for clinical trials of cognition-enhancing interventions for schizophrenia. Normative data for the MCCB has been previously obtained in the U.S. Extrapolation of these normative data to different countries may be problematic due to the translation of the different tests, as well as potential cultural influences. We present the process of obtaining normative data for the MCCB in Spain with administration of the battery to a general community standardization sample. In addition, we examine the influence of age, gender, and educational level on test performance. The MCCB was administered to a total sample of 210 healthy volunteers, at three Spanish sites. For each site, recruitment of the sample was stratified according to age, gender, and educational level. Our findings indicate significant age, gender, and education effects on the normative data for the MCCB in Spain, which are comparable to those effects described for the original standardized English version in the U.S. The fact that the normative data are comparable, and that the variables age, gender, and education have a similar influence on performance, supports the robustness of the MCCB for use in different countries.

Original languageEnglish
Pages (from-to)279-284
Number of pages6
JournalSchizophrenia Research
Volume134
Issue number2-3
DOIs
StatePublished - Feb 2012
Externally publishedYes

Bibliographical note

Funding Information:
This research was supported in part by grant PI080514 (Fondo de Investigaciones Sanitarias, FIS) and by the Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM) of the Instituto de Salud Carlos III.

Funding

This research was supported in part by grant PI080514 (Fondo de Investigaciones Sanitarias, FIS) and by the Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM) of the Instituto de Salud Carlos III.

Funders
Instituto de Salud Carlos III
Centro de Investigación Biomédica en Red de Salud Mental

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

    Keywords

    • Cognition
    • MATRICS
    • MCCB
    • Schizophrenia

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