The lymphoproliferative disease virus of turkeys represents a distinct class of avian type-C retrovirus

Ayelet Chajut, Ronit Sarid, Abraham Yaniv, Gary W. Smythers, Steven R. Tronick, Arnona Gazit

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The lymphoproliferative disease virus of turkeys (LPDV) is the etiological agent of a rapidly developing lymphoproliferative process in turkeys. To better understand the genetic relationships of LPDV to other retroviruses we determined the nucleotide sequence of its pol gene. Comparative computer analyses of the deduced amino acid sequences of the reverse transcriptase and integrase domains within pol established that LPDV represents a distinct class of avian retroviruses that is most closely related to the avian leukemia-sarcoma viruses.

Original languageEnglish
Pages (from-to)349-354
Number of pages6
JournalGene
Volume122
Issue number2
DOIs
StatePublished - 15 Dec 1992
Externally publishedYes

Bibliographical note

Funding Information:
We thank Dr. S.A. Aaronson for his continued support and encouragement.T his study was supported in part by a project grant from the Fund for Basic Research administered by the Israel Academy of Sciences and Humanities, the Israel Cancer Research Fund and the Israel Cancer Association.

Funding

We thank Dr. S.A. Aaronson for his continued support and encouragement.T his study was supported in part by a project grant from the Fund for Basic Research administered by the Israel Academy of Sciences and Humanities, the Israel Cancer Research Fund and the Israel Cancer Association.

FundersFunder number
Fund for Basic Research
Israel Cancer Research Fund
Israel Academy of Sciences and Humanities
Israel Cancer Association

    Keywords

    • Recombinant DNA
    • genetic relatedness
    • integrase
    • pol
    • reverse transcriptase

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