The Inverted U: Exploring the Interconnectedness of Movement and Cognitive Function Across the Lifespan

  • Gerry Leisman
  • , Rahela Alfasi
  • , Oded Meiron
  • , Amedeo D'Angiulli

Research output: Contribution to journalReview articlepeer-review

Abstract

The “inverted U” relationship between movement and cognition throughout the human lifespan highlights the intricate interplay between physical activity and cognitive function. This relationship posits that an optimal level of physical activity maximizes cognitive function, while insufficient activity can lead to suboptimal cognitive outcomes. This phenomenon is observed from fetal development to old age, emphasizing the importance of maintaining a balance in physical activity for overall well-being. During fetal development, maternal physical activity positively influences fetal brain growth, laying the foundation for future cognitive and physical functioning. As the child develops, regular physical activity supports improvements in key cognitive functions such as attention, memory, and executive function abilities essential for learning and academic success. In adulthood, maintaining an active lifestyle continues to play a central role in preserving cognitive abilities and reducing the risk of neurodegenerative diseases such as Alzheimer's. The inverted U model suggests that optimal cognitive functioning is achieved at moderate levels of physical activity, while too little activity can be detrimental. In older adulthood, regular physical activity is vital for maintaining cognitive function, slowing cognitive decline, and improving quality of life. In summary, understanding the balance between physical activity and cognition across the lifespan is essential for promoting cognitive resilience and sustained well-being. This article is categorized under: Cognitive Biology > Cognitive Development Psychology > Development and Aging Psychology > Learning.

Original languageEnglish
Article numbere70020
JournalWiley Interdisciplinary Reviews: Cognitive Science
Volume17
Issue number1
DOIs
StatePublished - 1 Jan 2026

Bibliographical note

Publisher Copyright:
© 2026 The Author(s). WIREs Cognitive Science published by Wiley Periodicals LLC.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • adolescence
  • aging
  • childhood
  • cognition
  • fetal cognition
  • human development
  • infancy
  • inverted U
  • learning
  • movement

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