The hydrogenation of β-hydroxy-γfluoro-γ-ethylenic esters as an efficient approach to the fluorohydrin substructure

Karine Lucet-Levannier, Jean Paul Lellouche, Charles Mioskowski, Florence Schneider, Claude Cassagne

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

A novel high-yielding preparation of the fluorohydrin moiety is depicted based on the reductive hydrogenation of β-hydroxy-γ-fluoro-γ-ethylenic esters. Several useful homogeneous as well heterogeneous conditions are disclosed and discussed in this communication.

Original languageEnglish
Pages (from-to)2007-2010
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number12
DOIs
StatePublished - 18 Mar 1996
Externally publishedYes

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