The Geriatric Scoring System (GSS) in meningioma patients - Validation

Or Cohen-Inbar, Gil E. Sviri, Jean F. Soustiel, Menashe Zaaroor

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


Background: Meningiomas are the most common primary brain tumor, the incidence of which rises with age. The Geriatric Scoring System (GSS) was constructed in an attempt to answer which elderly subpopulation will benefit from a surgical intervention in terms of their overall physical and functional state of health. The GSS incorporates different prognostic indicators, both clinical and radiological, for risk stratification. Objective: The purpose of the study was to validate the previously defined GSS for the evaluation and risk stratification of elderly patients suffering from intracranial meningioma. Methods: One hundred and twenty patients aged over 65 years admitted to the RAMBAM Medical Center with meningiomas during the years 2005-2010 were characterized, forming an independent cohort. We report the presenting symptoms, chronic illness and radiological features, as well as perioperative and long-term follow-up results up to 5 years after the surgery. Results: Nine outcome parameters were tested against the GSS score on admission. Survival, Barthel Index, Karnofsky Performance Scale (KPS), consciousness expressed by the Glasgow Coma Scale (GCS) [14] score 5 years after surgery, recurrence within and beyond 12 months of surgery, the length of hospitalization both overall and in a neurosurgical intensive care unit. A GSS score higher than 16 was associated with a significantly more favorable outcome. Conclusion: The present results suggest that common experience-based considerations may be optimized and implemented into a simple scoring system that in turn may allow for outcome prediction and evidence-based decision making.

Original languageEnglish
Pages (from-to)1501-1508
Number of pages8
JournalActa Neurochirurgica
Issue number7
StatePublished - Jul 2011
Externally publishedYes


  • Elderly
  • Evidence based medicine
  • GSS score
  • Meningioma
  • Prognosis


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