The effect of bilateral transcranial direct current stimulation on early auditory processing in schizophrenia: a preliminary study

Walter Dunn; Yuri Rassovsky; Jonathan Wynn; Allan D. Wu; Marco Iacoboni; Gerhard Hellemann; Michael F. Green

doi:10.1007/s00702-017-1752-5

The effect of bilateral transcranial direct current stimulation on early auditory processing in schizophrenia: a preliminary study

Walter Dunn, Yuri Rassovsky, Jonathan Wynn, Allan D. Wu, Marco Iacoboni, Gerhard Hellemann, Michael F. Green

Department of Psychology

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Transcranial direct current stimulation (tDCS) was applied bilaterally over the auditory cortex in 12 schizophrenia patients to modulate early auditory processing. Performance on a tone discrimination task (tone-matching task—TMT) and auditory mismatch negativity were assessed after counterbalanced anodal, cathodal, and sham tDCS. Cathodal stimulation improved TMT performance (p < 0.03) compared to sham condition. Post-hoc analyses revealed a stimulation condition by negative symptom interaction in which greater negative symptoms were associated with a better TMT performance after anodal tDCS.

Original language	English
Pages (from-to)	1145-1149
Number of pages	5
Journal	Journal of Neural Transmission
Volume	124
Issue number	9
DOIs	https://doi.org/10.1007/s00702-017-1752-5
State	Published - 1 Sep 2017

Bibliographical note

Publisher Copyright:
© 2017, Springer-Verlag GmbH Austria (outside the USA).

Funding

Funding This study was funded by the Veterans Administration (VA) Desert Pacific Veterans Integrated Service Network 22 (VISN 22) Mental Illness Research, Education, and Clinical Center (MIRECC).

Funders	Funder number
MIRECC
Pacific Veterans Integrated Service Network 22
Veterans Administration
NIH Clinical Center

Keywords

Auditory processing
Mismatch negativity
Schizophrenia
Tone-matching task
Transcranial direct current stimulation
tDCS

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s00702-017-1752-5

Cite this

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abstract = "Transcranial direct current stimulation (tDCS) was applied bilaterally over the auditory cortex in 12 schizophrenia patients to modulate early auditory processing. Performance on a tone discrimination task (tone-matching task—TMT) and auditory mismatch negativity were assessed after counterbalanced anodal, cathodal, and sham tDCS. Cathodal stimulation improved TMT performance (p < 0.03) compared to sham condition. Post-hoc analyses revealed a stimulation condition by negative symptom interaction in which greater negative symptoms were associated with a better TMT performance after anodal tDCS.",

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The effect of bilateral transcranial direct current stimulation on early auditory processing in schizophrenia: a preliminary study

Abstract

Bibliographical note

Funding

Keywords

UN SDGs

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