Abstract
Whether neurons encode information through their spike rates, their activity times or both is an ongoing debate in systems neuroscience. Here, we tested whether humans can discriminate between a pair of temporal odor mixtures (TOMs) composed of the same two components delivered in rapid succession in either one temporal order or its reverse. These TOMs presumably activate the same olfactory neurons but at different times and thus differ mainly in the time of neuron activation. We found that most participants could hardly discriminate between TOMs, although they easily discriminated between a TOM and one of its components. By contrast, participants succeeded in discriminating between the TOMs when they were notified of their successive nature in advance. We thus suggest that the time of glomerulus activation can be exploited to extract odor-related information, although it does not change the odor perception substantially, as should be expected from an odor code per se.
Original language | English |
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Article number | e49734 |
Journal | eLife |
Volume | 9 |
DOIs | |
State | Published - 7 Feb 2020 |
Bibliographical note
Publisher Copyright:© Perl et al.
Funding
We would like to extend our thanks to Shani Agron for help with GCMS analyses. We are indebted to Noam Sobel for helpful insights provided during the preparation of this manuscript. This study was supported by the ISF- 204/17 grant.
Funders | Funder number |
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Israel Science Foundation |