Targeting angiogenesis in the treatment of multiple myeloma

Najib Dally, Elizabeth Eshel

Research output: Contribution to journalArticlepeer-review

Abstract

Multiple Myeloma (MM) remains an incurable disease. Scientific understanding of the biology and influence of the microenvironment in disease progression and outcome has led to treatment improvements by targeting angiogene-sis. Reviews of the underlying biology and meta-analyses of the clinical data tend to be mutually exclusive. This mini-review highlights important data regarding angiogenesis in MM as well as the drugs currently used to target angiogenesis in its treatment.

Original languageEnglish
Pages (from-to)39-47
Number of pages9
JournalCurrent Angiogenesis
Volume3
Issue number1
DOIs
StatePublished - 1 Jan 2014

Bibliographical note

Publisher Copyright:
© 2014 Bentham Science Publishers

Keywords

  • Angiogenesis inhibitors
  • Anti angiogenetic agents
  • Anti-angiogenic effects
  • Immunomodulation
  • Multiple myeloma

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