Tailor made magnetic nanolights: Fabrication to cancer theranostics applications

Poushali Das, Sayan Ganguly, Shlomo Margel, Aharon Gedanken

Research output: Contribution to journalReview articlepeer-review

98 Scopus citations

Abstract

Nanoparticles having magnetic and fluorescent properties could be considered as a gift to materials scientists due to their unique magneto-optical qualities. Multiple component particles can overcome challenges related with a single component and unveil bifunctional/multifunctional features that can enlarge their applications in diagnostic imaging agents and therapeutic delivery vehicles. Bifunctional nanoparticles that have both luminescent and magnetic features are termed as magnetic nanolights. Herein, we present recent progress of magneto-fluorescent nanoparticles (quantum dots based magnetic nanoparticles, Janus particles, and heterocrystalline fluorescent magnetic materials), comprehensively describing fabrication strategies, types, and biomedical applications. In this review, our aim is not only to encompass the preparation strategies of these special types of magneto-fluorescent nanomaterials but also their extensive applications in bioimaging techniques, cancer therapy (targeted and hyperthermic), and sustained release of active agents (drugs, proteins, antibodies, hormones, enzymes, growth factors).

Original languageEnglish
Pages (from-to)6762-6796
Number of pages35
JournalNanoscale Advances
Volume3
Issue number24
DOIs
StatePublished - 7 Dec 2021

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry.

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