TY - JOUR
T1 - Tailor made magnetic nanolights
T2 - Fabrication to cancer theranostics applications
AU - Das, Poushali
AU - Ganguly, Sayan
AU - Margel, Shlomo
AU - Gedanken, Aharon
N1 - Publisher Copyright:
© The Royal Society of Chemistry.
PY - 2021/12/7
Y1 - 2021/12/7
N2 - Nanoparticles having magnetic and fluorescent properties could be considered as a gift to materials scientists due to their unique magneto-optical qualities. Multiple component particles can overcome challenges related with a single component and unveil bifunctional/multifunctional features that can enlarge their applications in diagnostic imaging agents and therapeutic delivery vehicles. Bifunctional nanoparticles that have both luminescent and magnetic features are termed as magnetic nanolights. Herein, we present recent progress of magneto-fluorescent nanoparticles (quantum dots based magnetic nanoparticles, Janus particles, and heterocrystalline fluorescent magnetic materials), comprehensively describing fabrication strategies, types, and biomedical applications. In this review, our aim is not only to encompass the preparation strategies of these special types of magneto-fluorescent nanomaterials but also their extensive applications in bioimaging techniques, cancer therapy (targeted and hyperthermic), and sustained release of active agents (drugs, proteins, antibodies, hormones, enzymes, growth factors).
AB - Nanoparticles having magnetic and fluorescent properties could be considered as a gift to materials scientists due to their unique magneto-optical qualities. Multiple component particles can overcome challenges related with a single component and unveil bifunctional/multifunctional features that can enlarge their applications in diagnostic imaging agents and therapeutic delivery vehicles. Bifunctional nanoparticles that have both luminescent and magnetic features are termed as magnetic nanolights. Herein, we present recent progress of magneto-fluorescent nanoparticles (quantum dots based magnetic nanoparticles, Janus particles, and heterocrystalline fluorescent magnetic materials), comprehensively describing fabrication strategies, types, and biomedical applications. In this review, our aim is not only to encompass the preparation strategies of these special types of magneto-fluorescent nanomaterials but also their extensive applications in bioimaging techniques, cancer therapy (targeted and hyperthermic), and sustained release of active agents (drugs, proteins, antibodies, hormones, enzymes, growth factors).
UR - http://www.scopus.com/inward/record.url?scp=85121208065&partnerID=8YFLogxK
U2 - 10.1039/d1na00447f
DO - 10.1039/d1na00447f
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C2 - 36132370
AN - SCOPUS:85121208065
SN - 2516-0230
VL - 3
SP - 6762
EP - 6796
JO - Nanoscale Advances
JF - Nanoscale Advances
IS - 24
ER -