Synthetic reverberating activity patterns embedded in networks of cortical neurons

R. Vardi, A. Wallach, E. Kopelowitz, M. Abeles, S. Marom, I. Kanter

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Synthetic reverberating activity patterns are experimentally generated by stimulation of a subset of neurons embedded in a spontaneously active network of cortical cells in vitro. The neurons are artificially connected by means of a conditional stimulation matrix, forming a synthetic local circuit with a predefined programmable connectivity and time delays. Possible uses of this experimental design are demonstrated, analyzing the sensitivity of these deterministic activity patterns to transmission delays and to the nature of ongoing network dynamics.

Original languageEnglish
Article number66002
JournalEPL
Volume97
Issue number6
DOIs
StatePublished - Mar 2012

Funding

FundersFunder number
Seventh Framework Programme269459

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