Synthesis of Steroidal Aziridines

R. Ikan, A. Mabktts, Z. Goldschmidt

Research output: Contribution to journalArticlepeer-review


Desmostanyl 3a-acetate (5) was synthesized from litocholic acid and converted into the aziridine 8, the essential steps being addition of iodine isocyanate to 5 which was converted to the corresponding carbamate 7. Treatment of 7 With alcoholic base formed the aziridine 8. Analogous sequence of reactions led to the formation of aziridine 9 from stigmasteryl acetate.

Original languageEnglish
Pages (from-to)1892-1894
Number of pages3
JournalJournal of Organic Chemistry
Issue number12
StatePublished - 1 Jun 1972
Externally publishedYes


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