Synthesis of photolabile protecting group (PPG) protected uronic acid building blocks: Applications in carbohydrate synthesis with the assistance of a continuous flow photoreactor

Varsha Tiwari, Adesh Kumar Singh, Priyanka Chaudhary, Peter H. Seeberger, Jeyakumar Kandasamy

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Photolabile protecting group (PPG) protected uronic acid building blocks were prepared and used for carbohydrate synthesis. Deprotection of the photolabile protecting group was achieved very efficiently by employing a continuous flow photoreactor under neutral conditions. Many conventional protecting groups were found to be stable during the photo-cleavage of the 2-nitrobenzyl group at 355 nm in methanol.

Original languageEnglish
Pages (from-to)3859-3863
Number of pages5
JournalOrganic Chemistry Frontiers
Volume6
Issue number23
DOIs
StatePublished - 7 Dec 2019
Externally publishedYes

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