TY - JOUR
T1 - Synthesis of N‐[N‐L‐γ‐glutamyl‐L‐cysteinyl‐(carbonyl‐14C)]‐glycine (glutathione‐14C) and of [Cys‐14CO]‐(5S,6R)‐LTC4
AU - Parent, P.
AU - Leborgne, F.
AU - Lellouche, J. P.
AU - Beaucourt, J. P.
AU - Vanhove, A.
PY - 1990/6
Y1 - 1990/6
N2 - [Cys‐14CO]‐glutathione or N‐[N‐L‐γ‐glutamyl‐L‐cysteinyl‐14CO] glycine was prepared by chemical synthesis, with the L,L‐natural configuration and a radiochemical yield of 1% based on sodium [14C] cyanide. This labelled compound was used to obtain [Cys‐14CO] with a yield of 15%. [Cys‐14CO]‐glutathione and [Cys‐14CO]LTC4 had a specific activity of 50 mCi/mmol (1.85 GBq/mmol).
AB - [Cys‐14CO]‐glutathione or N‐[N‐L‐γ‐glutamyl‐L‐cysteinyl‐14CO] glycine was prepared by chemical synthesis, with the L,L‐natural configuration and a radiochemical yield of 1% based on sodium [14C] cyanide. This labelled compound was used to obtain [Cys‐14CO] with a yield of 15%. [Cys‐14CO]‐glutathione and [Cys‐14CO]LTC4 had a specific activity of 50 mCi/mmol (1.85 GBq/mmol).
UR - http://www.scopus.com/inward/record.url?scp=0025150427&partnerID=8YFLogxK
U2 - 10.1002/jlcr.2580280603
DO - 10.1002/jlcr.2580280603
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AN - SCOPUS:0025150427
SN - 0362-4803
VL - 28
SP - 633
EP - 644
JO - Journal of Labelled Compounds and Radiopharmaceuticals
JF - Journal of Labelled Compounds and Radiopharmaceuticals
IS - 6
ER -