Synthesis and characterization of polymeric implant for kyphoplasty

Boaz Mizrahi; Ronen Shavit; Abraham J. Domb

doi:10.1002/jbm.b.31043

Synthesis and characterization of polymeric implant for kyphoplasty

Boaz Mizrahi, Ronen Shavit, Abraham J. Domb

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Copolymers of methyl methacrylate (MMA) and lauryl methacrylate (LMA) were prepared to obtain injectable ductile materials to be used in restoring vertebra height in kyphoplasty. Copolymers with M_w in the range of 130,000 and polydispersity of 1.8 were obtained. Several aspects of the effect of adding LMA monomers were examined including intrinsic viscosity, thermal properties, mechanical properties, and the ability to be injected under high pressure. By increasing the amount of LMA, the ductility of the polymer was increased, accompanied by a decrease in Young's modulus and strength. The copolymer with monomers ratio (MMA:LMA) 1:1 v/v possessed the most suitable mechanical properties and injectability, which may have potential clinical use in orthopedics.

Original language	English
Pages (from-to)	466-473
Number of pages	8
Journal	Journal of Biomedical Materials Research - Part B Applied Biomaterials
Volume	86
Issue number	2
DOIs	https://doi.org/10.1002/jbm.b.31043
State	Published - Aug 2008
Externally published	Yes

Keywords

Acrylic bone cement
Kyphoplasty
Lauryl methacrylic
Mechanical properties
Methyl methacrylate

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10.1002/jbm.b.31043

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AU - Domb, Abraham J.

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Synthesis and characterization of polymeric implant for kyphoplasty

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