Abstract
Gold nanoparticles (GNPs) have garnered significant attention in biomedical applications, particularly as versatile platforms for drug delivery and targeted therapy. The conjugation of GNPs with antibodies offers a promising strategy to enhance their specificity and efficacy in various therapeutic approaches. In this study, we focus on synthesizing different types of GNPs conjugated with antibodies and investigate the influence of various synthesis methods on nanoparticle characterization. The results demonstrated that different synthesis methods lead to different degrees of antibody conjugation on the GNP surface and to varied efficiency on biosystems. This work has the potential to outline design principles that could positively affect the development of targeted nanotherapeutics for various biomedical applications.
| Original language | English |
|---|---|
| Title of host publication | Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI |
| Editors | Dror Fixler, Sebastian Wachsmann-Hogiu |
| Publisher | SPIE |
| ISBN (Electronic) | 9781510669758 |
| DOIs | |
| State | Published - 2024 |
| Event | Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI 2024 - San Francisco, United States Duration: 28 Jan 2024 → … |
Publication series
| Name | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
|---|---|
| Volume | 12858 |
| ISSN (Print) | 1605-7422 |
Conference
| Conference | Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI 2024 |
|---|---|
| Country/Territory | United States |
| City | San Francisco |
| Period | 28/01/24 → … |
Bibliographical note
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