Synaptogenesis and myelination in dissociated cerebral microcarrier cell cultures

A. Shahar, S. Reuveny, A. Amir, M. Kotler, A. Mizrahi

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


A new approach for cultivating dissociated cerebral neurons is described. It is based on a rapid attachment of neurons to the DEAE‐cellulose cylindrical MC and their subsequent interconnection to form cell‐MC conglomerates. Intensive fiber growth followed by synaptogenesis and progressive myelin formation are indicative of optimal conditions of nutrition and oxygenation.

Original languageEnglish
Pages (from-to)339-348
Number of pages10
JournalJournal of Neuroscience Research
Issue number3
StatePublished - 1983
Externally publishedYes


  • conglomerates
  • microcarriers
  • myelin
  • neurons
  • synapses


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