Surface-modified protein nanospheres as potential antiviral agents

Dana Baram-Pinto; Michal Richman; Aharon Gedanken; Shai Rahimipour; Ronit Sarid

doi:10.1039/c2cc33448h

Surface-modified protein nanospheres as potential antiviral agents

Dana Baram-Pinto, Michal Richman, Aharon Gedanken, Shai Rahimipour, Ronit Sarid

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

A novel application of surface-modified protein nanospheres as potential antiviral agents is illustrated. By using a single-step sonochemical process, bovine serum albumin nanospheres were generated, whose surface was covalently conjugated with mercaptoethane sulfonate to chemically and electrostatically mimic cellular heparan sulfate. The nanospheres effectively inhibited HSV-1 infection.

Original language	English
Pages (from-to)	8359-8361
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	67
DOIs	https://doi.org/10.1039/c2cc33448h
State	Published - 25 Jul 2012

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Surface-modified protein nanospheres as potential antiviral agents

Abstract

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