Surface-Engineered Magnetic Nanoparticles (Iron Oxides) and Their Therapeutic Applications

In recent years, there has been a lot of interest in biodegradable surface-engineered iron oxide nanoparticles (IONPs) because they could be used in drug delivery and other biomedical fields. This chapter gives an overview of the current state of research on how to make biodegradable IONPs, how to engineer their surfaces, and how to make them work for drug delivery and other biomedical applications. Because these nanoparticles are biodegradable, they will break down and leave the body in a safe way, reducing worries about toxicity. Also, the surface of IONPs can be changed to make them more stable, biocompatible, and able to target specific cells or tissues. This makes it easier for drugs to get to where they need to go. The review talks about how natural polymers, peptides, and targeting ligands are used to change the surface, as well as how these changes affect the physicochemical properties and therapeutic functions of biodegradable IONPs. The chapter also talks about recent improvements in the use of biodegradable IONPs for imaging, hyperthermia, and tissue engineering, among other medical uses. Lastly, problems and hopes for the future of biodegradable surface-engineered IONPs in the biomedical field are talked about. Overall, this review gives an in-depth look at the current research on biodegradable surface-engineered IONPs, focusing on their potential for drug delivery and other biomedical uses. It also talks about where this field, which is changing quickly, might go in the future.